盐酸帕唑帕尼

Description

Pazopanib Hydrochloride · CAS 635702-64-6 · C21H24ClN7O2S. UNII 33Y9ANM545.

Identification

CAS Registry Number	635702-64-6
PubChem CID	11525740
Molecular formula	C21H24ClN7O2S
IUPAC name	5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;hydrochloride
UNII (FDA)	33Y9ANM545

Computed Descriptors

Molecular Weight	474.0
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	5
Exact Mass	473.1400719
Monoisotopic Mass	473.1400719
Topological Polar Surface Area	127
Heavy Atom Count	32
Formal Charge	0
Complexity	717

GHS Hazard Classification

Reported hazard statements	H351 (16.7%), H360 (16.7%), H361 (66.7%), H372 (66.7%), H400 (33.3%), H411 (66.7%)

Documented Uses

• Pazopanib hydrochloride is approved to treat adults with:
• • Renal cell carcinoma (a type of kidney cancer) that is advanced.
• • Soft tissue sarcoma that is advanced. It is used in patients who have already been treated with chemotherapy.
• Pazopanib hydrochloride is also being studied in the treatment of other types of cancer.
• Cytochrome P450 2C8 Inhibitors [MoA]; Kinase Inhibitor [EPC]; Cytochrome P450 2D6 Inhibitors [MoA]; Protein Kinase Inhibitors [MoA]; Cytochrome P450 3A4 Inhibitors [MoA]

Synonyms

Pazopanib hydrochloride; 635702-64-6; pazopanib HCl; UNII-33Y9ANM545; pazopanib monohydrochloride; Pazopanib (as hydrochloride); 33Y9ANM545; CHEBI:71217; DTXSID70212956; NSC737754; PAZOPANIB HYDROCHLORIDE (MART.); PAZOPANIB HYDROCHLORIDE [MART.]; RefChem:55813; DTXCID00135447; Votrient; Pazopanib HCl (GW786034 HCl)

Frequently Asked Questions

What are the CAS number and molecular formula of Pazopanib Hydrochloride?

CAS 635702-64-6; molecular formula C21H24ClN7O2S; molecular weight — g/mol.

What other names is Pazopanib Hydrochloride known by?

Pazopanib hydrochloride, 635702-64-6, pazopanib HCl, UNII-33Y9ANM545, pazopanib monohydrochloride, Pazopanib (as hydrochloride).

Is Pazopanib Hydrochloride classified as hazardous?

Hazard statements reported: H351, H360, H361, H372, H400.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.