五氟利多

Description

Penfluridol · CAS 26864-56-2 · C28H27ClF5NO. UNII 25TLU22Q8H.

Identification

CAS Registry Number	26864-56-2
PubChem CID	33630
Molecular formula	C28H27ClF5NO
IUPAC name	1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]piperidin-4-ol
UNII (FDA)	25TLU22Q8H

Computed Descriptors

Molecular Weight	524.0
XLogP3	7.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	7
Exact Mass	523.1701330
Monoisotopic Mass	523.1701330
Topological Polar Surface Area	23.5
Heavy Atom Count	36
Formal Charge	0

Physical description & handling notes

• 216.67 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 217.53 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 219.1 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H301 (100%)

Documented Uses

• Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
• N05AG - Diphenylbutylpiperidine derivatives
• QN05AG - Diphenylbutylpiperidine derivatives

Synonyms

PENFLURIDOL; 26864-56-2; Semap; Penfluridolum; McN-JR-16,341; R-16341; DTXSID5049021; MCN-JR-16341; R 16341; NSC-759179; 25TLU22Q8H; 4-Piperidinol, 1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)-; R 16,341; DTXCID6028947; 4-Piperidinol, 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-; RefChem:859405

Frequently Asked Questions

What are the CAS number and molecular formula of Penfluridol?

CAS 26864-56-2; molecular formula C28H27ClF5NO; molecular weight — g/mol.

What other names is Penfluridol known by?

PENFLURIDOL, 26864-56-2, Semap, Penfluridolum, McN-JR-16,341, R-16341.

Is Penfluridol classified as hazardous?

Hazard statements reported: H301.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.