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Description

pethidine hydrochloride · CAS 50-13-5 · C15H22ClNO2. UNII N8E7F7Q170.

Identification

CAS Registry Number	50-13-5
PubChem CID	5750
Molecular formula	C15H22ClNO2
IUPAC name	ethyl 1-methyl-4-phenylpiperidine-4-carboxylate;hydrochloride
UNII (FDA)	N8E7F7Q170

Computed Descriptors

Molecular Weight	283.79
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	283.1339066
Monoisotopic Mass	283.1339066
Topological Polar Surface Area	29.5
Heavy Atom Count	19
Formal Charge	0
Complexity	276

GHS Hazard Classification

Reported hazard statements	H301 (98.6%), H317 (25.7%), H331 (25.7%), H334 (25.7%), H372 (23%), H373 (23%)

Documented Uses

• Used to control moderate to severe pain.
• Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS.
• Agents that are administered in association with anesthetics to increase effectiveness, improve delivery, or decrease required dosage.
• Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS.
• Full Opioid Agonists [MoA]; Opioid Agonist [EPC]
• Meperidine is metabolized in the liver by hydrolysis to meperidinic acid followed by partial conjugation with glucuronic acid. Meperidine also undergoes N-demethylation to normeperidine, which then undergoes hydrolysis and partial conjugation. Normeperidine is about half as potent as meperidine, but it has twice the CNS stimulation effects. Route of Elimination: Excreted in the urine. The proportion of drug that is excreted unchanged or as metabolites is dependent on pH. When urine pH is uncontrolled, 5-30% of the

Synonyms

MEPERIDINE HYDROCHLORIDE; Pethidine hydrochloride; 50-13-5; Antiduol; Centralgin; Dispadol; Dolantal; Dolestine; Dolaren; Algil; Meperidine Hcl; Antidurol; Doloneurine; Petantin; Piridosal; Dolenal

Frequently Asked Questions

What are the CAS number and molecular formula of pethidine hydrochloride?

CAS 50-13-5; molecular formula C15H22ClNO2; molecular weight — g/mol.

What other names is pethidine hydrochloride known by?

MEPERIDINE HYDROCHLORIDE, Pethidine hydrochloride, 50-13-5, Antiduol, Centralgin, Dispadol.

Is pethidine hydrochloride classified as hazardous?

Hazard statements reported: H301, H317, H331, H334, H372.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.