酒石酸匹马范色林

Description

Pimavanserin tartrate · CAS 706782-28-7 · C54H74F2N6O10. UNII NA83F1SJSR.

Identification

CAS Registry Number	706782-28-7
PubChem CID	11672491
Molecular formula	C54H74F2N6O10
IUPAC name	(2R,3R)-2,3-dihydroxybutanedioic acid;bis(1-[(4-fluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea)
UNII (FDA)	NA83F1SJSR

Computed Descriptors

Molecular Weight	1005.2
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	19
Exact Mass	1004.54344890
Monoisotopic Mass	1004.54344890
Topological Polar Surface Area	205
Heavy Atom Count	72
Formal Charge	0
Complexity	657

Regulatory Status

GHS notification summary	50% (1 / 2)

GHS Hazard Classification

GHS notification summary	50% (1 / 2)
Reported hazard statements	H302, H332 (50%), H317 (50%), H318 (50%)

Documented Uses

• Breast Feeding; Lactation; Milk, Human; Antiparkinson Agents; Antipsychotic Agents; Serotonin 5-HT2 Receptor Antagonists
• Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists.
• Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
• Drugs that bind to but do not activate SEROTONIN 5-HT2 RECEPTORS, thereby blocking the actions of SEROTONIN or SEROTONIN 5-HT2 RECEPTOR AGONISTS. Included under this heading are antagonists for one or more specific 5-HT2 receptor subtypes.

Synonyms

Pimavanserin tartrate; 706782-28-7; Nuplazid; NA83F1SJSR; CHEBI:133014; DTXSID50220958; RefChem:59075; DTXCID80143449; UNII-NA83F1SJSR; pimavanserin hemitartrate; Pimavanserin tartrate [USAN]; MFCD09970919; Pimavanserin Dihydroxysuccinate(2:1); Pimavanserin tartrate (USAN); 1-(4-fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea hemi((2R,3R)-2,3-dihydroxysuccinate); 706782-28-7 (tartrate)

Frequently Asked Questions

What are the CAS number and molecular formula of Pimavanserin tartrate?

CAS 706782-28-7; molecular formula C54H74F2N6O10; molecular weight — g/mol.

What other names is Pimavanserin tartrate known by?

Pimavanserin tartrate, 706782-28-7, Nuplazid, NA83F1SJSR, CHEBI:133014, DTXSID50220958.

Is Pimavanserin tartrate classified as hazardous?

50% of GHS notifications report no hazard classification (1 of 2).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.