匹马范色林

匹马范色林（CAS 706779-91-1）的公开数据库记录，列此仅供独立核对。

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• Pimavanserin is indicated for the treatment of hallucinations and delusions associated with Parkinson’s disease psychosis.
• Pimavanserin is an atypical antipsychotic that received FDA approval in the U.S. in 2016 for hallucinations and delusions that accompany Parkinson disease psychosis (PDP). It is the first and only FDA-approved medication for PDP. It had initially received Breakthrough Therapy status from the FDA in 2014. In the phase III clinical trial that paved the way for FDA approval, patients receiving pimavanserin demonstrated significant improvement in the frequency and/or severity of hallucinations and/or delusions without
• Pimavanserin is an atypical antipsychotic used in the treatment of hallucinations and delusions in patients with Parkinson disease and psychosis. Use of pimavanserin is associated with a low rate of serum enzyme elevations during therapy but it has not been linked to instances of clinically apparent acute liver injury.
• Breast Feeding; Lactation; Milk, Human; Antiparkinson Agents; Antipsychotic Agents; Serotonin 5-HT2 Receptor Antagonists
• Avoid grapefruit products. Dose adjustment may be necessary if taking grapefruit products or other CYP3A4 inhibitors.
• Avoid St. John's Wort. This may induce the CYP3A4 metabolism of pimavanserin, which may cause reduced efficacy.

它在各数据库里的别名

Pimavanserin; 706779-91-1; ACP-103; pimavanserina; pimavanserine; JZ963P0DIK; CHEBI:133017; DTXSID90990906; 1-[(4-fluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea; N-(4-Fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide; ACP 103; N-(4-Fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl)carbamide; 1-[(4-fluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)-3-{[4-(2-methylpropoxy)phenyl]methyl}urea; pimavanserinum; 1-((4-fluorophenyl)methyl)-1-(1-methylpiperidin-4-yl)-3-((4-(2-methylpropoxy)phenyl)methyl)urea; RefChem:59074

计算机算出的分子描述符

数据库摘要

Pimavanserin · CAS 706779-91-1 · C25H34FN3O2. UNII JZ963P0DIK. 沸点: 604.2±55.0; 熔点: 117-119; Dissociation Constants: 13.52±0.46.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。