苯丙醇胺

Description

Phenylpropanolamine · CAS 14838-15-4 · C9H13NO. UNII 33RU150WUN. Melting Point: 190-194 °C; Melting Point: 101-101.5 °C; LogP: 0.67.

Identification

CAS Registry Number	14838-15-4
PubChem CID	10297
Molecular formula	C9H13NO
IUPAC name	(1R,2S)-2-amino-1-phenylpropan-1-ol
UNII (FDA)	33RU150WUN

Computed Descriptors

Molecular Weight	151.21
XLogP3	0.8
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	2
Exact Mass	151.099714038
Monoisotopic Mass	151.099714038
Topological Polar Surface Area	46.3
Heavy Atom Count	11
Formal Charge	0

Physical & Chemical Properties

Melting Point	190-194 °C
Melting Point	101-101.5 °C
LogP	0.67
LogP	log Kow = 0.67
Dissociation Constants	9.44 (at 20 °C)

Physical description & handling notes

• White, crystalline powder
• Slight aromatic odor
• Solid. Mol wt: 187.69, mp: 194 °C. Soluble in water. /Hydrochloride/
• Freely soluble
• Freely soluble in water and alcohol
• When heated to decomposition it emits very toxic fumes of nitroxides.

GHS Hazard Classification

Reported hazard statements	H302 (100%), H315 (100%), H319 (100%), H335 (100%)

Documented Uses

• Used as a raw material in cold and diet tablets /Hydrochloride/
• THERAP CAT: Decongestant (nasal); anorexic; in treatment of urinary incontinence
• THERAP CAT (vet): In treatment of urinary incontinence in cats and dogs; decongestant (nasal)
• Phenylpropanolamine, its salts, optical isomers, and salts of optical isomers
• A chemical specified by regulation that, in addition to legitimate uses, is used in manufacturing a controlled substance in violation of the Act and is important to the manufacture of a controlled substance. (21 eCFR 1310.02)
• Phenylpropanolamine is prepared by converting propiophenone to the alpha-oximino derivative with an alkyl nitrate, followed by catalytic hydrogenation, using a Pd or Pt catalyst.

Synonyms

phenylpropanolamine; Propadrine; Phenylpropanolaminum; Phenylfenesin; Rinexin; Fansia; Fenilpropanolamina; 14838-15-4; erythro-2-Amino-1-phenyl-1-propanol; 33RU150WUN; CHEBI:8104; NSC17704; Benzenemethanol, alpha-(1-aminoethyl)-, (R*,S*)-(+-)-; NSC-9920; RefChem:56356; Phenylpropanolamine 1534

Frequently Asked Questions

What are the CAS number and molecular formula of Phenylpropanolamine?

CAS 14838-15-4; molecular formula C9H13NO; molecular weight — g/mol.

What other names is Phenylpropanolamine known by?

phenylpropanolamine, Propadrine, Phenylpropanolaminum, Phenylfenesin, Rinexin, Fansia.

Is Phenylpropanolamine classified as hazardous?

Hazard statements reported: H302, H315, H319, H335.

What are the key physical properties of Phenylpropanolamine?

Melting Point: 190-194 °C; Melting Point: 101-101.5 °C; LogP: 0.67; LogP: log Kow = 0.67.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.