丙美卡因

Description

Proparacaine · CAS 499-67-2 · C16H26N2O3. UNII B4OB0JHI1X. Melting Point: 182-183.3 °C; Melting Point: 182 - 183.3 °C; Solubility: 1.39e+00 g/L.

Identification

CAS Registry Number	499-67-2
PubChem CID	4935
Molecular formula	C16H26N2O3
IUPAC name	2-(diethylamino)ethyl 3-amino-4-propoxybenzoate
UNII (FDA)	B4OB0JHI1X

Computed Descriptors

Molecular Weight	294.39
XLogP3	2.7
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	10
Exact Mass	294.19434270
Monoisotopic Mass	294.19434270
Topological Polar Surface Area	64.8
Heavy Atom Count	21
Formal Charge	0

Physical & Chemical Properties

Melting Point	182-183.3 °C
Melting Point	182 - 183.3 °C
Solubility	1.39e+00 g/L
LogP	2.5
Dissociation Constants	3.2

Physical description & handling notes

• Solid
• Soluble
• Proparacaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action. More specifically, proparacaine appears to bind or antagonize the function of voltage gated sodium channels.

Documented Uses

• Used as an ophthalmic anesthetic (as eye drops) to reduce pain and discomfort during procedures involving the eye. [Wikipedia]
• Used as a local (ophthalmic) anesthetic.
• Proparacaine (Class: Other Substances, Added Date: 05-2016)
• Physiologic Effects [PE] - Local Anesthesia
• Established Pharmacologic Class [EPC] - Local Anesthetic
• Proparacaine is a Local Anesthetic. The physiologic effect of proparacaine is by means of Local Anesthesia.

Synonyms

proparacaine; Proxymetacaine; 499-67-2; 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate; Proximetacainum; Proximetacaina; Prossimetacaina; Proxymetacainum; 3-Amino-4-propoxybenzoic acid 2-(diethylamino)ethyl ester; BENZOIC ACID, 3-AMINO-4-PROPOXY-, 2-(DIETHYLAMINO)ETHYL ESTER; B4OB0JHI1X; DTXSID30198146; proxymethacaine; RefChem:58606; DTXCID60120637; S01HA04

Frequently Asked Questions

What are the CAS number and molecular formula of Proparacaine?

CAS 499-67-2; molecular formula C16H26N2O3; molecular weight — g/mol.

What other names is Proparacaine known by?

proparacaine, Proxymetacaine, 499-67-2, 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate, Proximetacainum, Proximetacaina.

What are the key physical properties of Proparacaine?

Melting Point: 182-183.3 °C; Melting Point: 182 - 183.3 °C; Solubility: 1.39e+00 g/L; LogP: 2.5.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.