帕瑞肽

Description

Pasireotide · CAS 396091-73-9 · C58H66N10O9. UNII 98H1T17066.

Identification

CAS Registry Number	396091-73-9
PubChem CID	9941444
Molecular formula	C58H66N10O9
IUPAC name	[(3S,6S,9S,12R,15S,18S,20R)-9-(4-aminobutyl)-3-benzyl-12-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-15-phenyl-6-[(4-phenylmethoxyphenyl)methyl]-1,4,7,10,13,16-hexazabicyclo[16.3.0]henicosan-20-yl] N-(2-aminoethyl)carbamate
UNII (FDA)	98H1T17066

Computed Descriptors

Molecular Weight	1047.2
XLogP3	4.7
Hydrogen Bond Donor Count	9
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	18
Exact Mass	1046.50142372
Monoisotopic Mass	1046.50142372
Topological Polar Surface Area	281
Heavy Atom Count	77
Formal Charge	0

Physical description & handling notes

• Soluble in water.
• Signifor® is an analogue of somatostatin that promotes reduced levels of cortisol secretion in Cushing's disease patients.

Documented Uses

• For the treatment of Cushing’s disease, specifically for those patients whom pituitary surgery has not been curative or is not an option.
• Breastfeeding; Lactation; Milk, Human; Hormones; Somatostatin Analogs and Derivatives
• Chemical substances having a specific regulatory effect on the activity of a certain organ or organs. The term was originally applied to substances secreted by various ENDOCRINE GLANDS and transported in the bloodstream to the target organs. It is sometimes extended to include those substances that are not produced by the endocrine glands but that have similar effects.
• Established Pharmacologic Class [EPC] - Somatostatin Analog
• Mechanisms of Action [MoA] - Somatostatin Receptor Agonists
• Pasireotide is a Somatostatin Analog. The mechanism of action of pasireotide is as a Somatostatin Receptor Agonist.

Synonyms

Pasireotide; 396091-73-9; SOM-230; SOM230; SOM 230; pasireotida; pasireotidum; CHEBI:72312; 98H1T17066; DTXSID501026040; RefChem:57495; H01CB05; DTXCID201510773; Pasireotide free base; Pasireotide [USAN:INN]; UNII-98H1T17066

Frequently Asked Questions

What are the CAS number and molecular formula of Pasireotide?

CAS 396091-73-9; molecular formula C58H66N10O9; molecular weight — g/mol.

What other names is Pasireotide known by?

Pasireotide, 396091-73-9, SOM-230, SOM230, SOM 230, pasireotida.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.