盐酸丙嗪

盐酸丙嗪（CAS 53-60-1）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

物理形态与操作说明

• >48.1 [ug/mL] (The mean of the results at pH 7.4)
• 161.4 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

这个物质在各数据库里的编号

数据库记载的用途

• Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly.
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, hydrochloride (1:1): INACTIVE
• Drugs used to prevent NAUSEA or VOMITING.
• Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
• Hepatic, primarily to N-desmethylpromazine and promazine sulfoxide. Absorption may be erratic and peak plasma concentrations show large interindividual differences. The metabolism occurs through oxidative processes mediated largely by hepatic microsomal and other drug metabolizing enzymes. Antoher step is the conjugaion with glucuronic acid. Other reactions include hydroxylation, demetylation, and sulfoxide formation. Moreover, metabolic alterations in side chain may also occur (A308, A631).

它在各数据库里的别名

PROMAZINE HYDROCHLORIDE; 53-60-1; Promazine Hcl; Starazin; Talofen; DTXSID4046949; NSC-17468; 10-(gamma-Dimethylamino-n-propyl)phenothiazine hydrochloride; U16EOR79U4; 10H-Phenothiazine-10-propanamine, N,N-dimethyl-, monohydrochloride; Promazine hydrochloride (USP); Promazine hydrochloride [USP]; 10-(3-(Dimethylamino)propyl)phenothiazine monohydrochloride; DTXCID2026949; NSC17468; CHEBI:8460

计算机算出的分子描述符

数据库摘要

promazine hydrochloride · CAS 53-60-1 · C17H21ClN2S. UNII U16EOR79U4.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。