苯妥沙明

Description

phenyltoloxamine · CAS 92-12-6 · C17H21NO. UNII K65LB6598J.

Identification

CAS Registry Number	92-12-6
PubChem CID	7077
Molecular formula	C17H21NO
IUPAC name	2-(2-benzylphenoxy)-N,N-dimethylethanamine
UNII (FDA)	K65LB6598J

Computed Descriptors

Molecular Weight	255.35
XLogP3	3.9
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	6
Exact Mass	255.162314293
Monoisotopic Mass	255.162314293
Topological Polar Surface Area	12.5
Heavy Atom Count	19
Formal Charge	0

GHS Hazard Classification

Reported hazard statements	H302 (100%), H315 (25%), H319 (25%)

Documented Uses

• Ethanamine, N,N-dimethyl-2-[2-(phenylmethyl)phenoxy]-: INACTIVE
• Phenyltoloxamine is a first generation antihistamine that is used for symptoms of the common cold and as a short acting sedative. Phenyltoloxamine has not been linked to instances of clinically apparent acute liver injury.
• Phenyltoloxamine (Class: Other Substances, Added Date: 12-1999)
• Readily accessible data regarding the absorption of phenyltoloxamine is not available. In fact, many first-generation H1 antihistamines have never had their pharmacokinetics (ie. absorption, distribution, metabolism, and elimination) optimally investigated.
• Readily accessible data regarding the primary route of elimination of phenyltoloxamine is not available. In fact, many first-generation H1 antihistamines have never had their pharmacokinetics (ie. absorption, distribution, metabolism, and elimination) optimally investigated.
• Readily accessible data regarding the volume of distribution of phenyltoloxamine is not available. In fact, many first-generation H1 antihistamines have never had their pharmacokinetics (ie. absorption, distribution, metabolism, and elimination) optimally investigated.

Synonyms

Phenyltoloxamine; 92-12-6; Bristamin; Histionex; Antin; Feniltoloxamina; Phenyltoloxaminum; 2-(2-Dimethylaminoethoxy)diphenylmethane; K65LB6598J; N,N-Dimethyl-2-(2-(phenylmethyl)phenoxy)ethanamine; N,N-Dimethyl-2-(alpha-phenyl-o-tolyloxy)ethylamine; Ethanamine, N,N-dimethyl-2-(2-(phenylmethyl)phenoxy)-; DTXSID9023467; Ethanamine, N,N-dimethyl-2-[2-(phenylmethyl)phenoxy]-; [2-(2-benzylphenoxy)ethyl]dimethylamine; (2-(2-benzylphenoxy)ethyl)dimethylamine

Frequently Asked Questions

What are the CAS number and molecular formula of phenyltoloxamine?

CAS 92-12-6; molecular formula C17H21NO; molecular weight — g/mol.

What other names is phenyltoloxamine known by?

Phenyltoloxamine, 92-12-6, Bristamin, Histionex, Antin, Feniltoloxamina.

Is phenyltoloxamine classified as hazardous?

Hazard statements reported: H302, H315, H319.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.