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Description

Propacetamol · CAS 66532-85-2 · C14H20N2O3. UNII 5CHW4JMR82. Boiling Point: 434.5ºC at 760 mmHg; LogP: 1.65.

Identification

CAS Registry Number	66532-85-2
PubChem CID	68865
Molecular formula	C14H20N2O3
IUPAC name	(4-acetamidophenyl) 2-(diethylamino)acetate
UNII (FDA)	5CHW4JMR82

Computed Descriptors

Molecular Weight	264.32
XLogP3	1.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	7
Exact Mass	264.14739250
Monoisotopic Mass	264.14739250
Topological Polar Surface Area	58.6
Heavy Atom Count	19
Formal Charge	0

Physical & Chemical Properties

Boiling Point	434.5ºC at 760 mmHg
LogP	1.65

Physical description & handling notes

• Soluble

Documented Uses

• This pro-drug of acetaminophen is administered intravenously. [Kanerva, p. 1829]
• Propacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.
• Compounds capable of relieving pain without the loss of CONSCIOUSNESS.
• Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
• N02B - Other analgesics and antipyretics
• QN02B - Other analgesics and antipyretics

Synonyms

Propacetamol; 66532-85-2; Propacetamolum; DTXSID3057800; 5CHW4JMR82; DTXCID7031589; 4-acetamidophenyl 2-(diethylamino)acetate; RefChem:176249; N02BE05; N, N-diethylglycine 4'-hydroxyacetanilide ester; 266-390-1; (4-acetamidophenyl) 2-(diethylamino)acetate; Propacetamol [INN]; Glycine, N,N-diethyl-, 4-(acetylamino)phenyl ester; Propacetamol (INN); Propacetamolum [Latin]

Frequently Asked Questions

What are the CAS number and molecular formula of Propacetamol?

CAS 66532-85-2; molecular formula C14H20N2O3; molecular weight — g/mol.

What other names is Propacetamol known by?

Propacetamol, 66532-85-2, Propacetamolum, DTXSID3057800, 5CHW4JMR82, DTXCID7031589.

What are the key physical properties of Propacetamol?

Boiling Point: 434.5ºC at 760 mmHg; LogP: 1.65.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.