甲磺酸瑞波西汀

Description

Reboxetine mesylate · CAS 98769-84-7 · C20H27NO6S. UNII L94J81YNNY.

Identification

CAS Registry Number	98769-84-7
PubChem CID	127150
Molecular formula	C20H27NO6S
IUPAC name	(2R)-2-[(R)-(2-ethoxyphenoxy)-phenylmethyl]morpholine;methanesulfonic acid
UNII (FDA)	L94J81YNNY

Computed Descriptors

Molecular Weight	409.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	6
Exact Mass	409.15590875
Monoisotopic Mass	409.15590875
Topological Polar Surface Area	102
Heavy Atom Count	28
Formal Charge	0
Complexity	425

GHS Hazard Classification

Reported hazard statements	H302 (100%), H360 (96.7%), H362 (96.7%), H373 (96.7%)

Documented Uses

• For the treatment of clinical depression.
• Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (ANTIDEPRESSIVE AGENTS, TRICYCLIC) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
• Reboxetine is metabolized by dealkylation, hydroxylation and oxidation followed by glucuronide or sulphate conjugation. It is metabolized by the cytochrome P450 CYP isoenzyme 3A4. Half Life: 12.5 hours

Synonyms

Reboxetine mesylate; 98769-84-7; Reboxetine mesilate; REBOXETINE METHANESULFONATE; FCE 20124; Prolift; DTXSID8045690; L94J81YNNY; PNU-155950E; Reboxetine methansulphonate; Reboxetine methanesulphonate; DTXCID6025690; FCE-20124; RefChem:178708; 2-((2-ethoxyphenoxy)benzyl)morpholine methanesulfonate; Reboxetine (mesylate)

Frequently Asked Questions

What are the CAS number and molecular formula of Reboxetine mesylate?

CAS 98769-84-7; molecular formula C20H27NO6S; molecular weight — g/mol.

What other names is Reboxetine mesylate known by?

Reboxetine mesylate, 98769-84-7, Reboxetine mesilate, REBOXETINE METHANESULFONATE, FCE 20124, Prolift.

Is Reboxetine mesylate classified as hazardous?

Hazard statements reported: H302, H360, H362, H373.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.