瑞莱巴坦

Description

Relebactam · CAS 1174018-99-5 · C12H20N4O6S. UNII 1OQF7TT3PF.

Identification

CAS Registry Number	1174018-99-5
PubChem CID	44129647
Molecular formula	C12H20N4O6S
IUPAC name	[(2S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate
UNII (FDA)	1OQF7TT3PF

Computed Descriptors

Molecular Weight	348.38
XLogP3	-3.6
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	4
Exact Mass	348.11035554
Monoisotopic Mass	348.11035554
Topological Polar Surface Area	137
Heavy Atom Count	23
Formal Charge	0

Physical description & handling notes

• Relebactam prevents the hydrolysis of [imipenem], allowing it to exert its bactericidal effect.

GHS Hazard Classification

Reported hazard statements	H373 (100%), H412 (100%)

Documented Uses

• Relebactam is indicated in combination with [imipenem] and [cilastatin] for the treatment of complicated urinary tract infections (including pyelonephritis), and complicated intra-abdominal infections caused by susceptible organisms in adults.
• Endogenous substances and drugs that inhibit or block the activity of BETA-LACTAMASES.
• Established Pharmacologic Class [EPC] - beta Lactamase Inhibitor
• Mechanisms of Action [MoA] - beta Lactamase Inhibitors
• Relebactam anhydrous is a beta Lactamase Inhibitor. The mechanism of action of relebactam anhydrous is as a beta Lactamase Inhibitor.
• Currently, relebactam is only available as an intravenous product; therefore, there is no relevant absorption data in the literature.

Synonyms

Relebactam; 1174018-99-5; MK-7655; Relebactam anhydrous; (-)-Relebactam anhydrous; 1OQF7TT3PF; [(2S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate; MK7655; Sulfuric acid mono-((2S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-1,6-diaza-bicyclo(3.2.1)oct-6-yl) ester; 1174020-13-3; RECARBRIO COMPONENT RELEBACTAM; MK-7655A COMPONENT RELEBACTAM; relebactamum; RECARBRIO COMPONENT RELEBACTAM MONOHYDRATE; ((2S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-1,6-diazabicyclo(3.2.1)octan-6-yl) hydrogen sulfate; RefChem:879223

Frequently Asked Questions

What are the CAS number and molecular formula of Relebactam?

CAS 1174018-99-5; molecular formula C12H20N4O6S; molecular weight — g/mol.

What other names is Relebactam known by?

Relebactam, 1174018-99-5, MK-7655, Relebactam anhydrous, (-)-Relebactam anhydrous, 1OQF7TT3PF.

Is Relebactam classified as hazardous?

Hazard statements reported: H373, H412.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.