链霉素

Description

streptomycin · CAS 57-92-1 · C21H39N7O12. UNII Y45QSO73OB. Boiling Point: 872.9∓75.0°C at 760 mmHg; Solubility: 1.28e+01 g/L; LogP: -2.53.

Identification

CAS Registry Number	57-92-1
PubChem CID	19649
Molecular formula	C21H39N7O12
IUPAC name	2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine
UNII (FDA)	Y45QSO73OB

Computed Descriptors

Molecular Weight	581.6
XLogP3	-8
Hydrogen Bond Donor Count	12
Hydrogen Bond Acceptor Count	15
Rotatable Bond Count	9
Exact Mass	581.26566970
Monoisotopic Mass	581.26566970
Topological Polar Surface Area	336
Heavy Atom Count	40
Formal Charge	0

Physical & Chemical Properties

Boiling Point	872.9∓75.0°C at 760 mmHg
Solubility	1.28e+01 g/L
LogP	-2.53
LogP	-6.4

Physical description & handling notes

• Solid
• Hygroscopic powder
• Odorless or nearly so
• Slightly bitter taste
• MW: 1457.383. Powder. MP: aproximately 230 °C /Streptomycin sulfate; 3810-74-0/
• White to light gray or pale buff powder; faint amine-like odor; solubility in mg/mL at about 28 °C: water greater than 20; methanol 0.85; ethanol 0.30; isopropanol 0.01; petroleum ether 0.015; carbon tetrachloride 0.035; ether 0.035, Practically insoluble in chloroform. /Streptomycin sesquisulfate/

Regulatory Status

Regulatory & Food Contact	ANTIMICROBIAL_AGENT: Veterinary Drug JECFA ADI: 0-0.05 mg/kg bw TRS 911-JECFA 58/26 FAS 39-JECFA 48/39 (1997)

GHS Hazard Classification

Reported hazard statements	H351 (34.9%), H361 (99.1%), H400, H410, H360

Documented Uses

• Anti-Bacterial Agents; Protein Synthesis Inhibitors
• Antibiotic/bactericide, fungicide, seed treatment/protectant.
• For more Uses (Complete) data for Streptomycin (7 total), please visit the HSDB record page.
• Use (kg; approx.) in Germany (2009): >25
• Consumption (g per capita; approx.) in Germany (2009): 0.000305
• Veterinary Drug -> ANTIMICROBIAL_AGENT -> JECFA Functional Classes

Synonyms

streptomycin; 57-92-1; Streptomycine; Agrimycin; Strepcen; Agrept; Gerox; Streptomicina; Streptomycinum; Streptomyzin; Hokko-mycin; Estreptomicina; CHEBI:17076; Y45QSO73OB; DTXSID4023597; NSC-14083

Frequently Asked Questions

What are the CAS number and molecular formula of streptomycin?

CAS 57-92-1; molecular formula C21H39N7O12; molecular weight — g/mol.

What other names is streptomycin known by?

streptomycin, 57-92-1, Streptomycine, Agrimycin, Strepcen, Agrept.

What is the regulatory status of streptomycin?

Documented regulatory listings: ANTIMICROBIAL_AGENT: Veterinary Drug; JECFA ADI: 0-0.05 mg/kg bw; TRS 911-JECFA 58/26.

Is streptomycin classified as hazardous?

Hazard statements reported: H351, H361, H400, H410, H360.

What are the key physical properties of streptomycin?

Boiling Point: 872.9∓75.0°C at 760 mmHg; Solubility: 1.28e+01 g/L; LogP: -2.53; LogP: -6.4.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.