盐酸特拉唑嗪二水合物

Description

Terazosin HCL dihydrate · CAS 70024-40-7 · C19H26ClN5O4. UNII 8QOP8Z9955.

Identification

CAS Registry Number	70024-40-7
PubChem CID	44383
Molecular formula	C19H26ClN5O4
IUPAC name	[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone;hydrochloride
UNII (FDA)	8QOP8Z9955

Computed Descriptors

Molecular Weight	423.9
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	4
Exact Mass	423.1673320
Monoisotopic Mass	423.1673320
Topological Polar Surface Area	103
Heavy Atom Count	29
Formal Charge	0
Complexity	544

Physical description & handling notes

• 195.7 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

GHS notification summary	25% (1 / 4)

GHS Hazard Classification

GHS notification summary	25% (1 / 4)
Reported hazard statements	H302 (50%), H319 (25%), H361 (25%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >75
• Consumption (g per capita; approx.) in Germany (2009): 0.000916
• Consumption (g per capita) in the USA (2002): 0.00144
• Drugs that bind to and block the activation of ADRENERGIC ALPHA-1 RECEPTORS.
• Drugs used in the treatment of urological conditions and diseases such as URINARY INCONTINENCE and URINARY TRACT INFECTIONS.

Synonyms

63074-08-8; Terazosin HCl; Terazosin hydrochloride anhydrous; Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-, monohydrochloride; 8QOP8Z9955; ABBOTT-45975 ANHYDROUS; RefChem:932721; 613-138-7; Hytrin; Vasocard; (4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone hydrochloride; MLS000040261; Terazosin (hydrochloride); MFCD00467965; 6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloride; Piperazine,1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, monohydrochloride

Frequently Asked Questions

What are the CAS number and molecular formula of Terazosin HCL dihydrate?

CAS 70024-40-7; molecular formula C19H26ClN5O4; molecular weight — g/mol.

What other names is Terazosin HCL dihydrate known by?

63074-08-8, Terazosin HCl, Terazosin hydrochloride anhydrous, Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-, monohydrochloride, 8QOP8Z9955, ABBOTT-45975 ANHYDROUS.

Is Terazosin HCL dihydrate classified as hazardous?

25% of GHS notifications report no hazard classification (1 of 4).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.