盐酸四氢唑啉

Description

tetrahydrozoline hydrochloride · CAS 522-48-5 · C13H17ClN2. UNII 0YZT43HS7D.

Identification

CAS Registry Number	522-48-5
PubChem CID	10648
Molecular formula	C13H17ClN2
IUPAC name	2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole;hydrochloride
UNII (FDA)	0YZT43HS7D

Computed Descriptors

Molecular Weight	236.74
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	1
Exact Mass	236.1080262
Monoisotopic Mass	236.1080262
Topological Polar Surface Area	24.4
Heavy Atom Count	16
Formal Charge	0
Complexity	259

Physical description & handling notes

• >35.5 [ug/mL] (The mean of the results at pH 7.4)
• 145.9 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H302 (100%), H315 (97.8%), H319 (97.8%), H335 (95.7%)

Documented Uses

• 1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, hydrochloride (1:1): ACTIVE
• Sterile solutions that are intended for instillation into the eye. It does not include solutions for cleaning eyeglasses or CONTACT LENS SOLUTIONS.
• Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
• Drugs designed to treat inflammation of the nasal passages, generally the result of an infection (more often than not the common cold) or an allergy related condition, e.g., hay fever. The inflammation involves swelling of the mucous membrane that lines the nasal passages and results in inordinate mucus production. The primary class of nasal decongestants are vasoconstrictor agents. (From PharmAssist, The Family Guide to Health and Medicine, 1993)

Synonyms

Tetrahydrozoline hydrochloride; 522-48-5; Tetrahydrozoline HCl; Tetryzoline hydrochloride; Tyzine; Vasopos; Tyzanol hydrochloride; Rhinopront; DTXSID7045316; 0YZT43HS7D; NSC-757339; 2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline hydrochloride; 2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline monohydrochloride; 1H-Imidazole, 4,5-dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-, monohydrochloride; CHEBI:9492; DTXCID5025316

Frequently Asked Questions

What are the CAS number and molecular formula of tetrahydrozoline hydrochloride?

CAS 522-48-5; molecular formula C13H17ClN2; molecular weight — g/mol.

What other names is tetrahydrozoline hydrochloride known by?

Tetrahydrozoline hydrochloride, 522-48-5, Tetrahydrozoline HCl, Tetryzoline hydrochloride, Tyzine, Vasopos.

Is tetrahydrozoline hydrochloride classified as hazardous?

Hazard statements reported: H302, H315, H319, H335.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.