柠檬酸托米芬

Description

TOREMIFENE CITRATE · CAS 89778-27-8 · C32H36ClNO8. UNII 2498Y783QT.

Identification

CAS Registry Number	89778-27-8
PubChem CID	3005572
Molecular formula	C32H36ClNO8
IUPAC name	2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid
UNII (FDA)	2498Y783QT

Computed Descriptors

Molecular Weight	598.1
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	14
Exact Mass	597.2129448
Monoisotopic Mass	597.2129448
Topological Polar Surface Area	145
Heavy Atom Count	42
Formal Charge	0
Complexity	710

Physical description & handling notes

• 4.4 [ug/mL] (The mean of the results at pH 7.4)
• 203 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

GHS Hazard Classification

Reported hazard statements	H302 (97.6%), H318 (92.7%), H400 (92.7%), H410 (92.7%)

Documented Uses

• A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63)
• Agents that inhibit BONE RESORPTION and/or favor BONE MINERALIZATION and BONE REGENERATION. They are used to heal BONE FRACTURES and to treat METABOLIC BONE DISEASES such as OSTEOPOROSIS.
• Selective Estrogen Receptor Modulators [MoA]; Estrogen Agonist/Antagonist [EPC]

Synonyms

TOREMIFENE CITRATE; 89778-27-8; DTXSID2021367; FC 1157a; FC-1157a; NSC-613680; NSC613680; 2498Y783QT; DTXCID301367; Citrate, Toremifene; RefChem:57434; Toremifene Citrate (1:1); FC1157a; 2-(p-((Z)-4-chloro-1,2-diphenyl-1-butenyl)-phenoxy)-N,N-dimethylethylamine citrate (1:1); Fareston; Toremifene citrate [USAN]

Frequently Asked Questions

What are the CAS number and molecular formula of TOREMIFENE CITRATE?

CAS 89778-27-8; molecular formula C32H36ClNO8; molecular weight — g/mol.

What other names is TOREMIFENE CITRATE known by?

TOREMIFENE CITRATE, 89778-27-8, DTXSID2021367, FC 1157a, FC-1157a, NSC-613680.

Is TOREMIFENE CITRATE classified as hazardous?

Hazard statements reported: H302, H318, H400, H410.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.