马来酸曲米帕明

马来酸曲米帕明（CAS 521-78-8）的公开数据库记录，列此仅供独立核对。

危险化学品分类与危害说明

物理形态与操作说明

• >61.6 [ug/mL] (The mean of the results at pH 7.4)
• 169.9 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

这个物质在各数据库里的编号

数据库记载的用途

• For the treatment of depression and depression accompanied by anxiety, agitation or sleep disturbance
• Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
• Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (ANTIDEPRESSIVE AGENTS, TRICYCLIC) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.

它在各数据库里的别名

Trimipramine maleate; 521-78-8; Trimipramine hydrogen maleate; Stangyl; DTXSID2045315; NSC-758386; 269K6498LD; 5-(3-(Dimethylamino)-2-methylpropyl)-10,11-dihydro-5H-dibenz(b,f)azepine maleate (1:1); DTXCID0025315; Rhotrimine; 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (Z)-2-butenedioate (1:1); CHEBI:35030; 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (2Z)-2-butenedioate (1:1); Trimipramine Maleate (1:1); RefChem:56472; 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)-2-methylpropyl)-, Maleate(1:1)

计算机算出的分子描述符

数据库摘要

trimipramine maleate · CAS 521-78-8 · C24H30N2O4. UNII 269K6498LD.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。