妥拉磺酰胺

Name: 妥拉磺酰胺
Brand: 济南圣和化工有限公司

CAS 1156-19-0C14H21N3O3SMW 311.40

妥拉磺酰胺，CAS 登记号 1156-19-0，由济南圣和化工有限公司现货供应，可提供纯度按批次COA提供(不公开发布) 的规格，下游主要用于有机化学品。支持样品与小批量试用，批量价格请联系我们获取，验收以批次 COA 为准。

规格参数

CAS号1156-19-0

分子式C14H21N3O3S

分子量311.40

熔点170-173 °C

LogP2.69

纯度按批次COA提供(不公开发布)

包装按订单/批次确认(不公开发布)

应用领域有机化学品

类别有机化学品

用途与场景

有机化学品

包装与供货

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

供货周期现货/按订单安排

文件与支持

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常见问题

在哪里能查到妥拉磺酰胺的 CAS 号？

本页已列出妥拉磺酰胺的 CAS 号：1156-19-0，可与随货 COA 核对。

可以提供哪些规格和包装？

常见纯度为按批次COA提供(不公开发布)，包装形式为按订单/批次确认(不公开发布)，特殊规格可在询价时说明。

妥拉磺酰胺一般用在什么产品里？

主要涉及有机化学品。

下单流程是怎样的？

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PubChem 公开数据

Description

tolazamide · CAS 1156-19-0 · C14H21N3O3S. UNII 9LT1BRO48Q. Melting Point: 170-173 °C; Melting Point: 170 - 173 °C; Solubility: 65.4.

Identification

CAS Registry Number	1156-19-0
PubChem CID	5503
Molecular formula	C14H21N3O3S
IUPAC name	1-(azepan-1-yl)-3-(4-methylphenyl)sulfonylurea
UNII (FDA)	9LT1BRO48Q

Computed Descriptors

Molecular Weight	311.40
XLogP3	1.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	311.13036271
Monoisotopic Mass	311.13036271
Topological Polar Surface Area	86.9
Heavy Atom Count	21
Formal Charge	0

Physical & Chemical Properties

Melting Point	170-173 °C
Melting Point	170 - 173 °C
Solubility	65.4
Solubility	In water, 65.4 mg/l @ 30 °C
Solubility	3.08e-01 g/L
LogP	2.69
LogP	log Kow= 2.69
LogP	2.5
LogP	2.34
Dissociation Constants	PKA @ 25 °C, 3.6; PKA @ 37.5 °C, 5.68

Physical description & handling notes

Tolazamide appears as white to off-white crystalline powder. Odorless or with a slight odor. (NTP, 1992)
Solid
Crystals
WHITE TO OFF-WHITE, CRYSTALLINE POWDER
ODORLESS OR HAS SLIGHT ODOR
322 to 336 °F (with decomposition) (NTP, 1992)

Regulatory Status

GHS notification summary	50% (1 / 2)

GHS Hazard Classification

GHS notification summary	50% (1 / 2)
Reported hazard statements	H370 (50%)

This chemical does not meet GHS hazard criteria for 50% (1 of 2) of reports.

H370 (50%): Causes damage to organs [Danger Specific target organ toxicity, single exposure]

Documented Uses

An orally effective hypoglycemic drug.
For use as an adjunct to diet to lower the blood glucose in patients with non-insulin dependent diabetes mellitus (Type II) whose hyperglycemia cannot be satisfactorily controlled by diet alone.
Prepn: Wright, Willette, J Med Pharm Chem 5, 815 (1962); Wright, British patent 887,886 (1962 to Upjohn).
METHYL P-TOLYLSULFONYLCARBAMATE IS CAUSED TO UNDERGO AMMONOLYSIS TYPE OF REACTION WITH 1-AMINOHEXAMETHYLENEIMINE, US PATENT 3,063,903.
Breast Feeding; Lactation; Milk, Human; Hypoglycemic Agents; Sulfonylurea Compounds
...THIS POTENT AGENT LACKS ANTIDIURETIC ACTION & MAY BE ESPECIALLY USEFUL IN TREATMENT OF PT WHO HAVE TENDENCY TO RETAIN WATER.

Synonyms

tolazamide; 1156-19-0; Tolinase; Norglycin; Tolanase; Tolazolamide; Diabewas; Tolazamida; Tolazamidum; 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea; NSC-70762; 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)urea; U-17835; N-(p-Toluenesulfonyl)-N'-hexamethyleniminourea; NCI-C03327; 4-(p-Tolylsulfonyl)-1,1-hexamethylenesemicarbazide

Frequently Asked Questions

What are the CAS number and molecular formula of tolazamide?

CAS 1156-19-0; molecular formula C14H21N3O3S; molecular weight — g/mol.

What other names is tolazamide known by?

tolazamide, 1156-19-0, Tolinase, Norglycin, Tolanase, Tolazolamide.

Is tolazamide classified as hazardous?

50% of GHS notifications report no hazard classification (1 of 2).

What are the key physical properties of tolazamide?

Melting Point: 170-173 °C; Melting Point: 170 - 173 °C; Solubility: 65.4; Solubility: In water, 65.4 mg/l @ 30 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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