替度鲁肽

替度鲁肽（CAS 197922-42-2）的公开数据库记录，列此仅供独立核对。

物理形态与操作说明

• 33 amino acid glucagon-like peptide-2 ... analog manufactured using a strain of Escherichia coli modified by recombinant DNA technology
• An enhancement of gastrointestinal fluid absorption (750-1000 mL/day) was observed following daily administrations of teduglutide. An increase in villus height and crypt depth of the intestinal mucosa was also noted. A decrease in fecal weight has also been observed. Teduglutide does not prolong the QTc interval.
• Subcutaneous injection: Powder for solution / 5mg/vial, Revestive
• Parenteral: For injection, for subcutaneous use, 5 mg (delivers 3.8 mg/0.38 mL) Gattex (available as a kit with sterile water for injection diluent, needles, syringes, and alcohol swabs), NPS Pharmaceuticals

这个物质在各数据库里的编号

数据库记载的用途

• Preparation: D.J. Drucker et al., World Intellectual Property Organization patent 9739031; edim, United States of America patent 5789379 (1997, 1998 both to Allelix).
• 33 amino acid glucagon-like peptide-2 ... analog manufactured using a strain of Escherichia coli modified by recombinant DNA technology
• Teduglutide is indicated for the treatment of adults and pediatric patients 1 year of age and older with Short Bowel Syndrome (SBS) who are dependent on parenteral support.
• Breast Feeding; Lactation; Milk, Human; Incretins; Glucagon-Like Peptide-1 Agonists; GLP-1 Agonists
• Gattex (teduglutide [rDNA origin]) for injection is indicated for the treatment of adult patients with short bowel syndrome (SBS) who are dependent on parenteral support. /Included in US product label/
• Teduglutide may increase intestinal absorption of drugs and should be used with caution in patients receiving concomitant oral therapy with CNS agents (e.g., benzodiazepines, antipsychotic agents), drugs that require dosage titration, or drugs that have a narrow therapeutic index.

它在各数据库里的别名

Teduglutide; Gattex; 197922-42-2; revestive; ALX-0600; Gattex Kit; Gly(2)-GLP-2; ALX 0600; Glucagon-like peptide II (2-glycine) (human); CHEBI:72305; 7M19191IKG; teduglutidum; RefChem:56099; A16AX08; DTXSID501027767; Glucagon-like Peptide II (2-glycine)

计算机算出的分子描述符

数据库摘要

Teduglutide · CAS 197922-42-2 · C164H252N44O55S. UNII 7M19191IKG.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。