替马沙星

Description

Temafloxacin · CAS 108319-06-8 · C21H18F3N3O3. UNII 1WZ12GTT67. LogP: -0.2.

Identification

CAS Registry Number	108319-06-8
PubChem CID	60021
Molecular formula	C21H18F3N3O3
IUPAC name	1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
UNII (FDA)	1WZ12GTT67

Computed Descriptors

Molecular Weight	417.4
XLogP3	0.6
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	3
Exact Mass	417.13002593
Monoisotopic Mass	417.13002593
Topological Polar Surface Area	72.9
Heavy Atom Count	30
Formal Charge	0

Physical & Chemical Properties

LogP	-0.2

Physical description & handling notes

• 193.0 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID7044132]
• 211.3 Ų [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID7044132]
• 209.4 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID7044132]

Documented Uses

• For the treatment of lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections.
• Substances that inhibit the growth or reproduction of BACTERIA.
• Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II.
• J - Antiinfectives for systemic use
• J01 - Antibacterials for systemic use
• J01M - Quinolone antibacterials

Synonyms

Temafloxacin; 108319-06-8; Temafloxacine; Omniflox; Temafloxacinum; 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid; A 62254; Temafloxacino; DTXSID7044132; T 1258; A-62254; 1WZ12GTT67; DTXCID5024132; RefChem:891341; CHEBI:77788; J01MA05

Frequently Asked Questions

What are the CAS number and molecular formula of Temafloxacin?

CAS 108319-06-8; molecular formula C21H18F3N3O3; molecular weight — g/mol.

What other names is Temafloxacin known by?

Temafloxacin, 108319-06-8, Temafloxacine, Omniflox, Temafloxacinum, 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid.

What are the key physical properties of Temafloxacin?

LogP: -0.2.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.