替卡西林

Description

ticarcillin · CAS 34787-01-4 · C15H16N2O6S2. UNII F93UJX4SWT. Solubility: 7.16e-02 g/L.

Identification

CAS Registry Number	34787-01-4
PubChem CID	36921
Molecular formula	C15H16N2O6S2
IUPAC name	(2S,5R,6R)-6-[[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
UNII (FDA)	F93UJX4SWT

Computed Descriptors

Molecular Weight	384.4
XLogP3	0.8
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	5
Exact Mass	384.04497858
Monoisotopic Mass	384.04497858
Topological Polar Surface Area	178
Heavy Atom Count	25
Formal Charge	0

Physical & Chemical Properties

Solubility	7.16e-02 g/L

Physical description & handling notes

• Solid
• Ticarcillin is a semisynthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. Ticarcillin is, however, susceptible to degradation by ß-lactamases, and therefore, the spectrum of activity does not normally include organisms which produce these enzymes.

GHS Hazard Classification

Reported hazard statements	H317 (100%), H334 (100%)

Documented Uses

• Consumption (g per capita) in the USA (2002): 0.0521
• For the treatment of bacterial infections.
• Ticarcillin is an extended-spectrum carboxypenicillin antibiotic and is used to treat moderate-to-severe infections due to susceptible organisms. Ticarcillin has been linked with idiosyncratic liver injury, but only rarely and as isolated case reports.
• Breast Feeding; Lactation; Milk, Human; Anti-Infective Agents; Antibacterial Agents; Penicillins
• Substances that inhibit the growth or reproduction of BACTERIA.
• Established Pharmacologic Class [EPC] - Penicillin-class Antibacterial

Synonyms

TICARCILLIN; 34787-01-4; Ticarcilina; Ticarcilline; Ticarcillinum; CHEBI:9587; F93UJX4SWT; alpha-carboxy-3-thienylmethylpenicillin; DTXSID0023668; BRL2288; Tarcil; Disodium, Ticarcillin; RefChem:389326; DTXCID503668; J01CA13; 252-213-5

Frequently Asked Questions

What are the CAS number and molecular formula of ticarcillin?

CAS 34787-01-4; molecular formula C15H16N2O6S2; molecular weight — g/mol.

What other names is ticarcillin known by?

TICARCILLIN, 34787-01-4, Ticarcilina, Ticarcilline, Ticarcillinum, CHEBI:9587.

Is ticarcillin classified as hazardous?

Hazard statements reported: H317, H334.

What are the key physical properties of ticarcillin?

Solubility: 7.16e-02 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.