他米巴罗汀

Description

Tamibarotene · CAS 94497-51-5 · C22H25NO3. UNII 08V52GZ3H9. Solubility: 5.75e-04 g/L.

Identification

CAS Registry Number	94497-51-5
PubChem CID	108143
Molecular formula	C22H25NO3
IUPAC name	4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid
UNII (FDA)	08V52GZ3H9

Computed Descriptors

Molecular Weight	351.4
XLogP3	5.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	351.18344366
Monoisotopic Mass	351.18344366
Topological Polar Surface Area	66.4
Heavy Atom Count	26
Formal Charge	0

Physical & Chemical Properties

Solubility	5.75e-04 g/L

Physical description & handling notes

• Solid

Documented Uses

• Investigated for use/treatment in leukemia (unspecified).
• Over 99%, predominantly to serum albumin.
• Tamibarotene is a specific agonist for retinoic acid receptor alpha/beta with possible binding to retinoid X receptors (RXR).

Synonyms

Tamibarotene; 94497-51-5; Am 80; retinobenzoic acid; 4-((5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl)benzoic acid; Am80; AM-80; Amnoid; 4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid; TOS-80T; INNO-507; DTXSID5046853; 4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid; TM-411; Tamibaroteno; NSC-608000

Frequently Asked Questions

What are the CAS number and molecular formula of Tamibarotene?

CAS 94497-51-5; molecular formula C22H25NO3; molecular weight — g/mol.

What other names is Tamibarotene known by?

Tamibarotene, 94497-51-5, Am 80, retinobenzoic acid, 4-((5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl)benzoic acid, Am80.

What are the key physical properties of Tamibarotene?

Solubility: 5.75e-04 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.