氢溴酸他泽美司他

氢溴酸他泽美司他（CAS 1467052-75-0）的公开数据库记录，列此仅供独立核对。

物理形态与操作说明

• Tazemetostat is a methyltransferase inhibitor that prevents hyper-trimethylation of histones and inhibits cancer cell de-differentiation. The duration of action is long as it is given twice daily. Patients should be counselled regarding the risk of secondary malignancies and embryo-fetal toxicity.

公开数据库收录的理化数据

这个物质在各数据库里的编号

数据库记载的用途

• Tazemetostat is a methyltransferase inhibitor and antineoplastic agent used in the therapy of advanced epithelioid sarcoma. Tazemetostat is associated with a moderate rate of transient serum enzyme elevations during therapy, but has not been implicated in cases of clinically apparent acute liver injury with jaundice.
• Established Pharmacologic Class [EPC] - Methyltransferase Inhibitor
• Mechanisms of Action [MoA] - Methyltransferase Inhibitors
• Mechanisms of Action [MoA] - Multidrug and Toxin Extrusion Transporter 1 Inhibitors
• Tazemetostat is a Methyltransferase Inhibitor. The mechanism of action of tazemetostat is as a Methyltransferase Inhibitor, and Multidrug and Toxin Extrusion Transporter 1 Inhibitor, and Multidrug and Toxin Extrusion Transporter 2 K Inhibitor.
• Methyltransferase Inhibitors [MoA]; Multidrug and Toxin Extrusion Transporter 1 Inhibitors [MoA]; Multidrug and Toxin Extrusion Transporter 2 K Inhibitors [MoA]; Methyltransferase Inhibitor [EPC]

它在各数据库里的别名

Tazemetostat; 1403254-99-8; EPZ-6438; EPZ6438; E7438; Tazemetostatum; E-7438; Q40W93WPE1; DTXSID201025831; RefChem:56753; DTXCID601510082; EPZ 6438; Tazemetostat (EPZ-6438); Tazemetostat [INN]; MFCD24849415; Tazemetostat [USAN]

计算机算出的分子描述符

数据库摘要

Tazemetostat hydrobromide · CAS 1467052-75-0 · C34H44N4O4. UNII Q40W93WPE1. LogP: 2.82.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。