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2-溴-α-麦角隐亭甲磺酸盐

CAS 22260-51-1C33H44BrN5O8SMW 750.7

2-溴-α-麦角隐亭甲磺酸盐(CAS 22260-51-1):分子式 C33H44BrN5O8S、分子量 750.7;类别 有机化学品。

产品描述

2-溴-α-麦角隐亭甲磺酸盐(CAS 22260-51-1)是一种有机化学品原料。其分子式 C33H44BrN5O8S 由 33 个碳、44 个氢、1 个溴、5 个氮、8 个氧、1 个硫 组成。 分子量约为 750.7。作为化工品采购代理与分销渠道,我们可在国内及跨境渠道为2-溴-α-麦角隐亭甲磺酸盐寻源比价,并安排小批量试样与批次采购;下单前提供完整 COA、质检报告与合规文件,验收以批次 COA 为准。

规格参数

CAS号22260-51-1
分子式C33H44BrN5O8S
分子量750.7
应用领域For the treatment of galactorrhea due to hyperprolactinemia、prolactin-dependent menstrual disorders and infertility、prolactin-secreting adenomas、prolactin-dependent male hypogonadism、as adjunct therapy to surgery or radiotherapy for acromegaly or as monotherapy is special cases、as monotherapy in early Parksinsonian Syndrome or as an adjunct with levodopa in advanced cases with motor complications. Bromocriptine has also been used off-label to treat restless legs syndrome and neuroleptic malignant syndrome. Bromocriptine is a semisynthetic ergotamine alkaloid that is a dopamine D2 agonist. It suppresses prolactin secretion and is used in the treatment of pituitary tumors
类别有机化学品

用途与场景

登记用途:For the treatment of galactorrhea due to hyperprolactinemia、prolactin-dependent menstrual disorders and infertility、prolactin-secreting adenomas、prolactin-dependent male hypogonadism、as adjunct therapy to surgery or radiotherapy for acromegaly or as monotherapy is special cases、as monotherapy in early Parksinsonian Syndrome or as an adjunct with levodopa in advanced cases with motor complications. Bromocriptine has also been used off-label to treat restless legs syndrome and neuroleptic malignant syndrome. Bromocriptine is a semisynthetic ergotamine alkaloid that is a dopamine D2 agonist. It suppresses prolactin secretion and is used in the treatment of pituitary tumors。

采购档案

这个产品是什么

2-溴-α-麦角隐亭甲磺酸盐 是一种以碳骨架为基础的有机化合物,登记 CAS 号为 22260-51-1,分子式 C33H44BrN5O8S(分子量 750.7),归属于有机化学品大类化工原料。

识别信息

登记 CAS 号:22260-51-1

其分子式 C33H44BrN5O8S 由 33 个碳、44 个氢、1 个溴、5 个氮、8 个氧、1 个硫 组成。

别名/同义词:2-溴-α-麦角隐亭甲磺酸盐 · 2-bromo-alpha-ergocryptine methane-sulfonate

所属分类:有机化学品

常见问题

2-溴-α-麦角隐亭甲磺酸盐 的 CAS 号是多少?

2-溴-α-麦角隐亭甲磺酸盐 的 CAS 登记号为 22260-51-1。

2-溴-α-麦角隐亭甲磺酸盐 的分子式与分子量是多少?

分子式 C33H44BrN5O8S,分子量 750.7。

2-溴-α-麦角隐亭甲磺酸盐 还有哪些别名?

别名/同义词:2-溴-α-麦角隐亭甲磺酸盐、2-bromo-alpha-ergocryptine methane-sulfonate。

2-溴-α-麦角隐亭甲磺酸盐 的登记用途是什么?

登记用途:For the treatment of galactorrhea due to hyperprolactinemia、prolactin-dependent menstrual disorders and infertility、prolactin-secreting adenomas、prolactin-dependent male hypogonadism、as adjunct therapy to surgery or radiotherapy for acromegaly or as monotherapy is special cases、as monotherapy in early Parksinsonian Syndrome or as an adjunct with levodopa in advanced cases with motor complications. Bromocriptine has also been used off-label to treat restless legs syndrome and neuroleptic malignant syndrome. Bromocriptine is a semisynthetic ergotamine alkaloid that is a dopamine D2 agonist. It suppresses prolactin secretion and is used in the treatment of pituitary tumors。

2-溴-α-麦角隐亭甲磺酸盐 属于哪个分类?

所属分类:有机化学品。

如何在 591daili.cn 采购 2-溴-α-麦角隐亭甲磺酸盐?

请在联系页面提交产品名称、CAS 号与数量,我们作为采购代理在国内及跨境渠道为您寻源比价,安排试样与批次采购,下单前提供 COA 与合规文件。

包装与单证

包装按订单确认,从实验室小包装到吨袋大货,随订单安排而非在页面上写死。每批随货附 COA 分析证书,可另提供 MSDS;若终端用途带有法规限度(食品接触、药品或化妆品),请在询价时说明执行标准,等级按该标准确定。

PubChem 公开数据

2-溴-α-麦角隐亭甲磺酸盐(CAS 22260-51-1)的公开数据库记录,列此仅供独立核对。

危险化学品分类与危害说明

Reported hazard statementsH302 (45.5%), H332 (36.4%), H361 (45.5%), H362 (18.2%), H400 (45.5%), H410 (72.7%)

H302 (45.5%): Harmful if swallowed [Warning Acute toxicity, oral]

H332 (36.4%): Harmful if inhaled [Warning Acute toxicity, inhalation]

物理形态与操作说明

  • 244.4 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

这个物质在各数据库里的编号

CAS Registry Number22260-51-1
PubChem CID31100
分子式C33H44BrN5O8S
IUPAC 名称(6aR,9R)-5-bromo-N-[(1S,2S,4R,7S)-2-hydroxy-7-(2-methylpropyl)-5,8-dioxo-4-propan-2-yl-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide;methanesulfonic acid
UNII(FDA)FFP983J3OD

数据库记载的用途

  • Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists.
  • Chemical substances which inhibit the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.
  • Drugs that bind to and activate dopamine receptors.
  • Ergot Derivative [EPC]; Ergolines [CS]
  • Completely metabolized by the liver, primarily by hydrolysis of the amide bond to produce lysergic acid and a peptide fragment, both inactive and non-toxic. Bromocriptine is metabolized by cytochrome P450 3A4 and excreted primarily in the feces via biliary secretion. Route of Elimination: Parent drug and metabolites are almost completely excreted via the liver, and only 6% eliminated via the kidney. Half Life: 2-8 hours

它在各数据库里的别名

BROMOCRIPTINE MESYLATE; 22260-51-1; Bromocriptine mesilate; Pravidel; Cycloset; Bagren; Bromocriptine methanesulfonate; CB-154 mesylate; Cb-154 mesilate; 2-Bromoergocryptine Mesylate; 2-Bromo-alpha-ergocryptine mesylate; DTXSID6020197; FFP983J3OD; NSC-755915; DTXCID00197; CHEBI:3182

计算机算出的分子描述符

分子量750.7
氢键供体数4
氢键受体数9
可旋转键数5
精确质量749.20940
单同位素质量749.20940
拓扑极性表面积181
重原子数48
形式电荷0
复杂度1320

数据库摘要

2-bromo-alpha-ergocryptine methane-sulfonate · CAS 22260-51-1 · C33H44BrN5O8S. UNII FFP983J3OD.

数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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English page: 2-bromo-alpha-ergocryptine methane-sulfonate

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