7-乙基-10-羟基喜树碱

Name: 7-乙基-10-羟基喜树碱
Brand: 济南圣和化工有限公司

CAS 86639-52-3C22H20N2O5MW 392.4

7-乙基-10-羟基喜树碱，CAS 登记号 86639-52-3，由济南圣和化工有限公司现货供应，可提供纯度按批次COA提供(不公开发布) 的规格，下游主要用于有机化学品。支持样品与小批量试用，批量价格请联系我们获取，验收以批次 COA 为准。

规格参数

CAS号86639-52-3

分子式C22H20N2O5

分子量392.4

LogP1.6

纯度按批次COA提供(不公开发布)

包装按订单/批次确认(不公开发布)

应用领域有机化学品

类别有机化学品

用途与场景

有机化学品

包装与供货

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

供货周期现货/按订单安排

文件与支持

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常见问题

在哪里能查到 7-乙基-10-羟基喜树碱的 CAS 号？

本页已列出 7-乙基-10-羟基喜树碱的 CAS 号：86639-52-3，可与随货 COA 核对。

可以提供哪些规格和包装？

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7-乙基-10-羟基喜树碱一般用在什么产品里？

主要涉及有机化学品。

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PubChem 公开数据

Description

7-Ethyl-10-hydroxycamptothecin · CAS 86639-52-3 · C22H20N2O5. UNII 0H43101T0J. LogP: 1.6.

Identification

CAS Registry Number	86639-52-3
PubChem CID	104842
Molecular formula	C22H20N2O5
IUPAC name	(19S)-10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
UNII (FDA)	0H43101T0J

Computed Descriptors

Molecular Weight	392.4
XLogP3	1.4
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	2
Exact Mass	392.13722174
Monoisotopic Mass	392.13722174
Topological Polar Surface Area	100
Heavy Atom Count	29
Formal Charge	0

Physical & Chemical Properties

LogP	1.6

GHS Hazard Classification

Reported hazard statements	H301 (75%), H341 (23.3%)

H301 (75%): Toxic if swallowed [Danger Acute toxicity, oral]

H341 (23.3%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]

Documented Uses

Investigated for use/treatment in colorectal cancer.
Compounds that inhibit the activity of DNA TOPOISOMERASE I.
The entrapment of SN-38 in lipsomes results in a more stable and more soluble form of the drug. This allows for increased affinity of SN-38 to lipid membranes and improved delivery of the drug to tumor sites. SN-38 is a highly effective cytotoxic topoisomerase I inhibitor.

Synonyms

7-Ethyl-10-hydroxycamptothecin; 86639-52-3; SN-38; SN 38 lactone; SN 38; 10-Hydroxy-7-ethylcamptothecin; NK-012; 7-Ethyl-10-hydroxy-20(S)-camptothecin; NK 012; NK012; 0H43101T0J; CAMPTOTHECIN, 7-ETHYL-10-HYDROXY-; CHEBI:8988; DTXSID4040399; (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione; (4S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Frequently Asked Questions

What are the CAS number and molecular formula of 7-Ethyl-10-hydroxycamptothecin?

CAS 86639-52-3; molecular formula C22H20N2O5; molecular weight — g/mol.

What other names is 7-Ethyl-10-hydroxycamptothecin known by?

7-Ethyl-10-hydroxycamptothecin, 86639-52-3, SN-38, SN 38 lactone, SN 38, 10-Hydroxy-7-ethylcamptothecin.

Is 7-Ethyl-10-hydroxycamptothecin classified as hazardous?

Hazard statements reported: H301, H341.

What are the key physical properties of 7-Ethyl-10-hydroxycamptothecin?

LogP: 1.6.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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