4-氨基马尿酸

Description

4-Aminohippuric acid · CAS 61-78-9 · C9H10N2O3. UNII Y79XT83BJ9. Melting Point: 199-200 °C; Melting Point: 198-199 °C; Melting Point: 198.5 °C.

Identification

CAS Registry Number	61-78-9
PubChem CID	2148
Molecular formula	C9H10N2O3
IUPAC name	2-[(4-aminobenzoyl)amino]acetic acid
UNII (FDA)	Y79XT83BJ9

Computed Descriptors

Molecular Weight	194.19
XLogP3	-0.9
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	194.06914219
Monoisotopic Mass	194.06914219
Topological Polar Surface Area	92.4
Heavy Atom Count	14
Formal Charge	0

Physical & Chemical Properties

Melting Point	199-200 °C
Melting Point	198-199 °C
Melting Point	198.5 °C
Solubility	13 mg/mL
Vapor Pressure	0.00000004 [mmHg]
LogP	-2.2
LogP	Log P= -0.89
LogP	-0.89
Dissociation Constants	3.83
Dissociation Constants	PKA: 4.0

Physical description & handling notes

• White solid; Discolors upon exposure to light; [Hawley] Off-white or white powder; [MSDSonline]
• Solid
• NEEDLES FROM HOT WATER
• PRISMS FROM WATER
• WHITE, CRYSTALLINE POWDER
• Slightly soluble

Regulatory Status

GHS notification summary	50% (1 / 2)

GHS Hazard Classification

GHS notification summary	50% (1 / 2)
Reported hazard statements	H301 (50%), H311 (50%)

Documented Uses

• Used as a diagnostic aid (renal function determination) and intermediate; [HSDB]
• ...BY REDN OF P-NITROHIPPURIC ACID.
• BY REACTING P-NITROBENZOYL CHLORIDE WITH GLYCINE & THEN REDUCING THE P-NITRO GROUP WITH TIN & HYDROCHLORIC ACID.
• Glycine, N-(4-aminobenzoyl)-: INACTIVE
• Used to measure effective renal plasma flow (ERPF) and to determine the functional capacity of the tubular excretory mechanism.
• MEDICATION: DIAGNOSTIC AID (RENAL FUNCTION DETERMINATION) /SRP: NOT COMMONLY USED IN RENAL FUNCTION TEST/

Synonyms

4-Aminohippuric acid; 61-78-9; aminohippuric acid; P-AMINOHIPPURIC ACID; N-(4-Aminobenzoyl)glycine; Glycine, N-(4-aminobenzoyl)-; Paha; para-Aminohippuric acid; Nefrotest; N-(p-Aminobenzoyl)glycine; PAH (amino acid); N-(para-aminobenzoyl)glycine; Hippuric acid, p-amino-; paraaminohippuric acid; 2-[(4-aminobenzoyl)amino]acetic acid; N-(p-Aminobenzoyl)aminoacetic acid

Frequently Asked Questions

What are the CAS number and molecular formula of 4-Aminohippuric acid?

CAS 61-78-9; molecular formula C9H10N2O3; molecular weight — g/mol.

What other names is 4-Aminohippuric acid known by?

4-Aminohippuric acid, 61-78-9, aminohippuric acid, P-AMINOHIPPURIC ACID, N-(4-Aminobenzoyl)glycine, Glycine, N-(4-aminobenzoyl)-.

Is 4-Aminohippuric acid classified as hazardous?

50% of GHS notifications report no hazard classification (1 of 2).

What are the key physical properties of 4-Aminohippuric acid?

Melting Point: 199-200 °C; Melting Point: 198-199 °C; Melting Point: 198.5 °C; Solubility: 13 mg/mL.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.