2-(1H)-喹啉酮

Description

2-(1H)-Quinolinone · CAS 59-31-4 · C9H7NO. UNII 803BHY7QWU. LogP: 1.32.

Identification

CAS Registry Number	59-31-4
PubChem CID	6038
Molecular formula	C9H7NO
IUPAC name	1H-quinolin-2-one
UNII (FDA)	803BHY7QWU

Computed Descriptors

Molecular Weight	145.16
XLogP3	1.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	145.052763847
Monoisotopic Mass	145.052763847
Topological Polar Surface Area	29.1
Heavy Atom Count	11
Formal Charge	0

Physical & Chemical Properties

LogP	1.32

Physical description & handling notes

• Light yellow crystalline solid; [Sigma-Aldrich MSDS]

GHS Hazard Classification

Reported hazard statements	H302 (92%), H315 (100%), H318 (52%), H319 (48%), H335 (98.7%)

Documented Uses

• Quinolones are a class of broad-spectrum antibiotics with excellent oral bioavailability and can be used to treat a wide variety of bacterial infections. Their clinical utility is restricted, particularly in the outpatient setting, due to their potential for severe side effects. Due to these safety concerns, quinolones are not recommended as first-line agents by the FDA if there are other available antibiotic options with less potential for severe adverse events. There are currently four generations of quinolones.

Synonyms

2-Hydroxyquinoline; 59-31-4; Carbostyril; Quinolin-2(1H)-one; 2(1H)-Quinolinone; 2-Quinolone; 1H-quinolin-2-one; o-Aminocinnamic acid lactam; alpha-Quinolone; 2-Quinolinone; 2(1H)-Quinolone; 803BHY7QWU; DTXSID1058769; NSC-156783; CHEBI:18289; RefChem:389257

Frequently Asked Questions

What are the CAS number and molecular formula of 2-(1H)-Quinolinone?

CAS 59-31-4; molecular formula C9H7NO; molecular weight — g/mol.

What other names is 2-(1H)-Quinolinone known by?

2-Hydroxyquinoline, 59-31-4, Carbostyril, Quinolin-2(1H)-one, 2(1H)-Quinolinone, 2-Quinolone.

Is 2-(1H)-Quinolinone classified as hazardous?

Hazard statements reported: H302, H315, H318, H319, H335.

What are the key physical properties of 2-(1H)-Quinolinone?

LogP: 1.32.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.