5-甲酰四氢叶酸

Q: 5-甲酰四氢叶酸 的 CAS 号是多少？

5-甲酰四氢叶酸 的 CAS 登记号为 58-05-9。

Q: 5-甲酰四氢叶酸 属于哪个分类？

所属分类：有机化学品。

CAS 58-05-9C20H23N7O7MW 473.4

5-甲酰四氢叶酸（CAS 58-05-9）：分子式 C20H23N7O7、分子量 473.4；类别有机化学品。

产品描述

5-甲酰四氢叶酸（CAS 58-05-9）是一种有机化学品原料。其分子式 C20H23N7O7 由 20 个碳、23 个氢、7 个氮、7 个氧组成。分子量约为 473.4。公开物性数据显示其熔点约 >260、LogP 约 -1.2。作为化工品采购代理与分销渠道，我们可在国内及跨境渠道为5-甲酰四氢叶酸寻源比价，并安排小批量试样与批次采购；下单前提供完整 COA、质检报告与合规文件，验收以批次 COA 为准。

规格参数

CAS号58-05-9

分子式C20H23N7O7

分子量473.4

熔点>260

LogP-1.2

应用领域Biochemical research、MEDICATION、For the treatment of osteosarcoma (after high dose methotrexate therapy). Used to diminish the toxicity and counteract the effects of impaired methotrexate elimination and of inadvertent overdosages of folic acid antagonists、and to treat megaloblastic anemias due to folic acid deficiency. Also used in combination with 5-fluorouracil to prolong survival in the palliative treatment of patients with advanced colorectal cancer. Used in cancer chemotherapy involving the drug methotrexate、Methods of Manufacturing: (1) Prepared by catalytic reduction of folic acid、(2) produced microbially

类别有机化学品

用途与场景

登记用途：Biochemical research、MEDICATION、For the treatment of osteosarcoma (after high dose methotrexate therapy). Used to diminish the toxicity and counteract the effects of impaired methotrexate elimination and of inadvertent overdosages of folic acid antagonists、and to treat megaloblastic anemias due to folic acid deficiency. Also used in combination with 5-fluorouracil to prolong survival in the palliative treatment of patients with advanced colorectal cancer. Used in cancer chemotherapy involving the drug methotrexate、Methods of Manufacturing: (1) Prepared by catalytic reduction of folic acid、(2) produced microbially。

采购档案

这个产品是什么

5-甲酰四氢叶酸是一种以碳骨架为基础的有机化合物，登记 CAS 号为 58-05-9，分子式 C20H23N7O7（分子量 473.4），归属于有机化学品大类化工原料。

识别信息

登记 CAS 号：58-05-9

其分子式 C20H23N7O7 由 20 个碳、23 个氢、7 个氮、7 个氧组成。

别名/同义词：5-甲酰四氢叶酸 · 5-formyltetrahydrofolic acid

所属分类：有机化学品

常见问题

5-甲酰四氢叶酸的 CAS 号是多少？

5-甲酰四氢叶酸的 CAS 登记号为 58-05-9。

5-甲酰四氢叶酸的分子式与分子量是多少？

分子式 C20H23N7O7，分子量 473.4。

5-甲酰四氢叶酸还有哪些别名？

别名/同义词：5-甲酰四氢叶酸、5-formyltetrahydrofolic acid。

5-甲酰四氢叶酸的登记用途是什么？

5-甲酰四氢叶酸属于哪个分类？

所属分类：有机化学品。

如何在 591daili.cn 采购 5-甲酰四氢叶酸？

请在联系页面提交产品名称、CAS 号与数量，我们作为采购代理在国内及跨境渠道为您寻源比价，安排试样与批次采购，下单前提供 COA 与合规文件。

包装与单证

包装按订单确认，从实验室小包装到吨袋大货，随订单安排而非在页面上写死。每批随货附 COA 分析证书，可另提供 MSDS；若终端用途带有法规限度（食品接触、药品或化妆品），请在询价时说明执行标准，等级按该标准确定。

PubChem 公开数据

5-甲酰四氢叶酸（CAS 58-05-9）的公开数据库记录，列此仅供独立核对。

物理形态与操作说明

Crystals from water with 3 mol of water of crystallization.
Sparingly soluble in water
2.3X10-21 mm Hg at 25 °C at 25 °C /Estimated/
log Kow = -4.45 /Estimated/
Henry's Law constant = 4.4X10-27 atm-cu m/mole at 25 °C /Estimated/
Leucovorin calcium injection, powder for injection, and tablets should be stored at 15-30 °C and protected from light. /Leucovorin calcium/

公开数据库收录的理化数据

熔点	>260
熔点	245 °C (decomp)
Collision Cross Section	201.7 Å² [M-H]-
Collision Cross Section	197.5 Å² [M+H]+

这个物质在各数据库里的编号

CAS Registry Number	58-05-9
PubChem CID	135403648
分子式	C20H23N7O7
IUPAC 名称	(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
UNII（FDA）	Q573I9DVLP

数据库记载的用途

For the treatment of osteosarcoma (after high dose methotrexate therapy). Used to diminish the toxicity and counteract the effects of impaired methotrexate elimination and of inadvertent overdosages of folic acid antagonists, and to treat megaloblastic anemias due to folic acid deficiency. Also used in combination with 5-fluorouracil to prolong survival in the palliative treatment of patients with advanced colorectal cancer. Used in cancer chemotherapy involving the drug methotrexate.
(1) Prepared by catalytic reduction of folic acid, (2) produced microbially.
Manufactoring: Shive, US 2741608 (1956 to Res. Corp.)
A member of the folic acid group of vitamins and a growth factor for the bacterium leuconostoc citroforum. Folinic acid is an important metabolite of folic acid and may be the active form in cellular metabolism.
Intermediate product of the metabolism of folic acid; the active form into which that acid is converted in the body, ascorbic acid being a necessary factor in the conversion process.
Information available in 2005 indicated that Leucovorin (folinic acid) was used in the manufacture of pharmaceutical preparations in the following countries: Belgium (1)

它在各数据库里的别名

folinic acid; leucovorin; 58-05-9; 5-Formyltetrahydrofolic acid; folinate; Folinic acid-SF; 5-formyltetrahydrofolate; Acide folinique; 5-Formyl-5,6,7,8-tetrahydrofolic acid; N5-Formyltetrahydrofolic acid; N5-Formyl-5,6,7,8-tetrahydrofolic acid; Q573I9DVLP; 5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid; DTXSID0048216; CHEBI:15640; (5-formyl-5,6,7,8-tetrahydropteroyl)glutamate

计算机算出的分子描述符

分子量	473.4
XLogP3	-1.2
氢键供体数	7
氢键受体数	10
可旋转键数	9
精确质量	473.16589610
单同位素质量	473.16589610
拓扑极性表面积	216
重原子数	34
形式电荷	0

数据库摘要

5-formyltetrahydrofolic acid · CAS 58-05-9 · C20H23N7O7. UNII Q573I9DVLP. 熔点: >260; 熔点: 245 °C (decomp); Collision Cross Section: 201.7 Å² [M-H]-.

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。

获取 5-甲酰四氢叶酸报价

供应商：济南圣和化工有限公司 · 一个工作日内回复。

邮件询价 WhatsApp