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4,4'-(五亚甲基二氧基)二苯甲脒双(2-羟基)

CAS 140-64-7C19H24N4O2.2C2H6O4SMW 592.7

4,4'-(五亚甲基二氧基)二苯甲脒双(2-羟基),CAS 登记号 140-64-7,由济南圣和化工有限公司现货供应,可提供纯度 按批次COA提供(不公开发布) 的规格,下游主要用于有机化学品。支持样品与小批量试用,批量价格请联系我们获取,验收以批次 COA 为准。

规格参数

CAS号140-64-7
分子式C19H24N4O2.2C2H6O4S
分子量592.7
熔点370 to 378 °F (NTP, 1992)
纯度按批次COA提供(不公开发布)
包装按订单/批次确认(不公开发布)
应用领域有机化学品
类别有机化学品

用途与场景

有机化学品

包装与供货

包装规格按订单/批次确认(不公开发布)
纯度规格按批次COA提供(不公开发布)
储存条件密封、阴凉干燥处保存
供货周期现货/按订单安排

文件与支持

每批随货提供 COA;可按需提供 MSDS 及技术文件。邮件注明产品名称与 CAS 号,一个工作日内回复报价。

常见问题

在哪里能查到 4,4'-(五亚甲基二氧基)二苯甲脒双(2-羟基) 的 CAS 号?

本页已列出 4,4'-(五亚甲基二氧基)二苯甲脒双(2-羟基) 的 CAS 号:140-64-7,可与随货 COA 核对。

可以提供哪些规格和包装?

常见纯度为 按批次COA提供(不公开发布),包装形式为 按订单/批次确认(不公开发布),特殊规格可在询价时说明。

4,4'-(五亚甲基二氧基)二苯甲脒双(2-羟基) 一般用在什么产品里?

主要涉及有机化学品。

下单流程是怎样的?

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PubChem 公开数据

Description

4,4'-(pentamethylenedioxy)dibenzamidine bis(2-hyd) · CAS 140-64-7 · C19H24N4O2.2C2H6O4S. UNII V2P3K60DA2. Melting Point: 370 to 378 °F (NTP, 1992); Solubility: Water > 30 (mg/mL); Solubility: 0.1 N HCl ~2.5 (mg/mL).

Identification

CAS Registry Number140-64-7
PubChem CID8813
Molecular formulaC19H24N4O2.2C2H6O4S
IUPAC name4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarboximidamide;bis(2-hydroxyethanesulfonic acid)
UNII (FDA)V2P3K60DA2

Computed Descriptors

Molecular Weight592.7
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count12
Rotatable Bond Count14
Exact Mass592.18728571
Monoisotopic Mass592.18728571
Topological Polar Surface Area284
Heavy Atom Count39
Formal Charge0
Complexity493

Physical & Chemical Properties

Melting Point370 to 378 °F (NTP, 1992)
SolubilityWater > 30 (mg/mL)
Solubility0.1 N HCl ~2.5 (mg/mL)
Solubility0.1 NaOH < 1 (mg/mL)
SolubilityEthanol (95 %) ~1.25 (mg/mL)
SolubilityMethanol ~1.25 (mg/mL)
SolubilityButanol < 1 (mg/mL)
SolubilityAcetonitrile < 1 (mg/mL)
SolubilityEthyl acetate < 1 (mg/mL)
SolubilityChloroform < 1 (mg/mL)

Physical description & handling notes

  • Pentamidine isethionate appears as odorless white or almost white crystals or powder. Odor also reported as a slight butyric odor. Very bitter taste. pH (5% aqueous solution) 4.5-6.5. (NTP, 1992)
  • greater than or equal to 100 mg/mL at 66 °F (NTP, 1992)
  • Acetate buffer, pH 4 ~2.5 (mg/mL)
  • Carbonate buffer, pH 9 < 1 (mg/mL)
  • Dimethyl acetamide ~15 (mg/mL)
  • Dimethyl sulfoxide ~15 (mg/mL)

GHS Hazard Classification

Reported hazard statementsH315 (100%), H317 (98.6%), H319 (100%), H335 (100%)

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

H317 (98.6%): May cause an allergic skin reaction [Warning Sensitization, Skin]

Documented Uses

  • For the treatment of pneumonia due to <i>Pneumocystis carinii</i>.
  • Pentamidine isethionate is an antifungal prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment and prevention of Pneumocystis pneumonia (PCP). The FDA-approved uses for pentamidine isethionate depend on the dosage form of the drug. Specifically, pentamidine isethionate injection is approved to treat PCP, and pentamidine isethionate inhalant is approved to prevent PCP in people with HIV who are at high risk of developing PCP.
  • PCP can be an opportunistic infection (OI) of HIV.
  • Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.
  • Substances that are destructive to protozoans.
  • Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA.

Synonyms

PENTAMIDINE ISETHIONATE; 140-64-7; Pentamidine diisethionate; 4,4'-(Pentane-1,5-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate); Pentamidine isetionate; Pentacarinat; Nebupent; Pentamidine diisetionate; Diamidine; Lomidin; Pneumopent; Lomidine isoethionate; PENTAM; USAF XR-10; DTXSID5023796; RP 2512

Frequently Asked Questions

What are the CAS number and molecular formula of 4,4'-(pentamethylenedioxy)dibenzamidine bis(2-hyd)?

CAS 140-64-7; molecular formula C19H24N4O2.2C2H6O4S; molecular weight — g/mol.

What other names is 4,4'-(pentamethylenedioxy)dibenzamidine bis(2-hyd) known by?

PENTAMIDINE ISETHIONATE, 140-64-7, Pentamidine diisethionate, 4,4'-(Pentane-1,5-diylbis(oxy))dibenzimidamide bis(2-hydroxyethanesulfonate), Pentamidine isetionate, Pentacarinat.

Is 4,4'-(pentamethylenedioxy)dibenzamidine bis(2-hyd) classified as hazardous?

Hazard statements reported: H315, H317, H319, H335.

What are the key physical properties of 4,4'-(pentamethylenedioxy)dibenzamidine bis(2-hyd)?

Melting Point: 370 to 378 °F (NTP, 1992); Solubility: Water > 30 (mg/mL); Solubility: 0.1 N HCl ~2.5 (mg/mL); Solubility: 0.1 NaOH < 1 (mg/mL).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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