1,4-双(2-乙基己基)2-磺基琥珀酸酯

Description

1,4-bis(2-ethylhexyl) 2-sulphosuccinate · CAS 10041-19-7 · C20H38O7S. UNII M7P27195AG. Melting Point: 153-157; LogP: 3.95.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Soluble
• 206.1 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID8022959]
• Docusate sodium is a laxative and an anionic detergent that supposedly promotes incorporation of water and fats into stool through a reduction in surface tension, resulting in softer fecal mass. Docusate's onset of action is 6-72 hours orally and 2-15 minutes rectally. The effects of docusate are thought to be exerted locally in the jejunum.

Documented Uses

• Surfactant, wetting agent, and solubilizer used in drugs, cosmetics, and foods; Has been used as a laxative and cerumenolytic; [ChemIDplus]
• Use (kg; approx.) in Germany (2009): >100
• Consumption (g per capita; approx.) in Germany (2009): 0.00122
• Butanedioic acid, 2-sulfo-, 1,4-bis(2-ethylhexyl) ester: ACTIVE
• Indicated for the treatment of constipation associated with dry, hard stools or opioid induced constipation. Though recently, pressure has been building to end the use of docusate over concerns of efficacy.
• Docusate is an orally available, over-the-counter laxative and stool softener used to treat or prevent constipation. Docusate has not been linked to serum enzyme elevations during therapy or to clinically apparent liver injury with jaundice.

Synonyms

DOCUSATE; Docusate hydrogen; 10041-19-7; Spolion 8; Diocto; Dioctylsulfosuccinsaeure; Docusates; DIOCTYLSULFOSUCCINATE; M7P27195AG; DTXSID1044279; Butanedioic acid, 2-sulfo-, 1,4-bis(2-ethylhexyl) ester; 1,4-Bis(2-ethylhexyloxy)-1,4-dioxo-2-butansulfonsaeure [IUPAC]; 1,4-Bis(2-ethylhexyloxy)-1,4-dioxo-2-butansulfonsaeure (IUPAC); DocQLace; Sulfosuccinate, Dioctyl; RefChem:55059

Frequently Asked Questions

What are the CAS number and molecular formula of 1,4-bis(2-ethylhexyl) 2-sulphosuccinate?

CAS 10041-19-7; molecular formula C20H38O7S; molecular weight — g/mol.

What other names is 1,4-bis(2-ethylhexyl) 2-sulphosuccinate known by?

DOCUSATE, Docusate hydrogen, 10041-19-7, Spolion 8, Diocto, Dioctylsulfosuccinsaeure.

What are the key physical properties of 1,4-bis(2-ethylhexyl) 2-sulphosuccinate?

Melting Point: 153-157; LogP: 3.95.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.