2-羟基地昔帕明

Description

2-Hydroxy Desipramine · CAS 1977-15-7 · C18H22N2O. UNII VO1Y07E90C.

Identification

CAS Registry Number	1977-15-7
PubChem CID	121249
Molecular formula	C18H22N2O
IUPAC name	11-[3-(methylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-3-ol
UNII (FDA)	VO1Y07E90C

Computed Descriptors

Molecular Weight	282.4
XLogP3	4.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	282.173213330
Monoisotopic Mass	282.173213330
Topological Polar Surface Area	35.5
Heavy Atom Count	21
Formal Charge	0

Documented Uses

• Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
• 2-hydroxy-desipramine is a known human metabolite of Desipramine.

Synonyms

2-Hydroxydesipramine; 1977-15-7; 2-Hydroxydesmethylimipramine; VO1Y07E90C; DTXSID20173467; 2-hydroxy-desipramine; 2-OH-DMI; RefChem:87516; DTXCID6095958; 2-Hydroxy Desipramine; Desipramine Impurity 1; 11-[3-(methylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-3-ol; 5-[3-(Methylamino)propyl]-10,11-dihydro-5H-dibenzo[b,f]azepin-2-ol; GP 36329; BRN 5587391; UNII-VO1Y07E90C

Frequently Asked Questions

What are the CAS number and molecular formula of 2-Hydroxy Desipramine?

CAS 1977-15-7; molecular formula C18H22N2O; molecular weight — g/mol.

What other names is 2-Hydroxy Desipramine known by?

2-Hydroxydesipramine, 1977-15-7, 2-Hydroxydesmethylimipramine, VO1Y07E90C, DTXSID20173467, 2-hydroxy-desipramine.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.