2-氨基-9H-吡啶并[2,3-b]吲哚

Description

2-Amino-9H-pyrido[2,3-b]indole · CAS 26148-68-5 · C11H9N3. UNII P0GZ1ICS6X. Melting Point: 202 °C; Melting Point: 202 - 203 °C; LogP: log Kow = 2.60.

Identification

CAS Registry Number	26148-68-5
PubChem CID	62805
Molecular formula	C11H9N3
IUPAC name	9H-pyrido[2,3-b]indol-2-amine
UNII (FDA)	P0GZ1ICS6X

Computed Descriptors

Molecular Weight	183.21
XLogP3	2.6
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	183.079647300
Monoisotopic Mass	183.079647300
Topological Polar Surface Area	54.7
Heavy Atom Count	14
Formal Charge	0

Physical & Chemical Properties

Melting Point	202 °C
Melting Point	202 - 203 °C
LogP	log Kow = 2.60
LogP	2.60
LogP	2.6

Physical description & handling notes

• Solid; [HSDB] Powder; [MP Biomedicals MSDS]
• Solid
• Crystalline solid
• Soluble in methanol and dimethyl sulfoxide
• When heated to decomposition it emits toxic fumes of /nitric oxides/.
• Stable under moderately acidic and alkaline conditions and in cold dilute aqueous solutions protected from light; Rapidly degrades in dilute hypochlorite; deactivated by weakly acidic nitrite solution with replacement of the 2-amino group by hydroxyl

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Cosmetics ingredient -> Fragrance

GHS Hazard Classification

Reported hazard statements	H340 (33.3%), H341 (66.7%), H351 (100%)

Documented Uses

• Found in grilled foods and cigarette smoke; Not used commercially; [HSDB]
• A-alpha-C is not used commercially.
• Cosmetics product ingredient: A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole)
• - Group 2B carcinogens identified by the International Agency for Research on Cancer
• - Known to cause cancer and listed under Health and Safety Code section 25249.8 of the California Safe Drinking Water and Toxic Enforcement Act of 1986 (Prop 65)
• Potential Health Impacts: Carcinogenicity

Synonyms

26148-68-5; 2-Amino-9H-pyrido[2,3-b]indole; 9H-pyrido[2,3-b]indol-2-amine; AalphaC; A-alpha-C; 2-Amino-alpha-carboline; Amino-alpha-carboline; 2-AMINO-9H-PYRIDO(2,3-B)INDOLE; Glob-P-2; 1H-Pyrido(2,3-b)indol-2-amine; P0GZ1ICS6X; 1H-Pyrido[2,3-b]indol-2-amine; 9H-Pyrido(2,3-b)indole, 2-amino-; BRN 0744369; DTXSID7020001; 9H-PYRIDO(2,3-B)INDOL-2-AMINE

Frequently Asked Questions

What are the CAS number and molecular formula of 2-Amino-9H-pyrido[2,3-b]indole?

CAS 26148-68-5; molecular formula C11H9N3; molecular weight — g/mol.

What other names is 2-Amino-9H-pyrido[2,3-b]indole known by?

26148-68-5, 2-Amino-9H-pyrido[2,3-b]indole, 9H-pyrido[2,3-b]indol-2-amine, AalphaC, A-alpha-C, 2-Amino-alpha-carboline.

What is the regulatory status of 2-Amino-9H-pyrido[2,3-b]indole?

Documented regulatory listings: CIR / INCI: Cosmetics ingredient -> Fragrance.

Is 2-Amino-9H-pyrido[2,3-b]indole classified as hazardous?

Hazard statements reported: H340, H341, H351.

What are the key physical properties of 2-Amino-9H-pyrido[2,3-b]indole?

Melting Point: 202 °C; Melting Point: 202 - 203 °C; LogP: log Kow = 2.60; LogP: 2.60.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.